HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 5-Butyl-2-chloro-nicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | 5-Butyl-2-chloro-nicotinic acid methyl ester | HCID 86616608 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Butyl-2-chloro-nicotinic acid | HCID 86616609 | — |
Reaction Steps
In analogy to the procedure described in example 124.1, 5-butyl-2-chloro-nicotinic acid methyl ester was treated with LiOH in THF to give 5-butyl-2-chloro-nicotinic acid as colorless crystals. MS: m/e=212.2 [M−H−].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572801B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-32bfb09433f54df3b3691c38bbe81b4c |
| Source note | uspto-grants-2009_08 |