HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-m-cresol → 4-[4-(4-Bromo-3-methyl-phenoxymethyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-m-cresol | HCID 72857 | — |
| Reactant | 4-(4-Hydroxymethylphenyl)piperidine-1-carboxylic acid t-butyl ester | HCID 22077056 | — |
| Product | 4-[4-(4-Bromo-3-methyl-phenoxymethyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 68812278 | — |
Reaction Steps
Mitsunobu coupling of 4-Bromo-3-methyl-phenol and 4-(4-Hydroxymethyl-phenyl)-piperidine-1-carboxylic acid tert-butyl ester as described in a previous example gave 4-[4-(4-Bromo-3-methyl-phenoxymethyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572811B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-4d2870a0b34142f49ac1226c2753490e |
| Source note | uspto-grants-2009_08 |