Isopropanol → HCID 57799606, compound
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[C:16]([CH3:18])[NH:15][N:14]=2)[N:3]=1.[CH3:19][CH:20]([OH:22])[CH3:21]>>[CH:20]([O:22][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[C:16]([CH3:18])[NH:15][N:14]=2)[N:3]=1)([CH3:21])[CH3:19]Participants
3
Procedure
Similar procedure as described in example 10 was used, starting from propan-2-ol, (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (1-isopropoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 283 (MH+).
Sources & evidence
- ORD record
- ord-67ecdd7995684a1499d7dc470571c123
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07572809B2
Reaction notes
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