Isopropanol → HCID 178458944, compound

HRID 2100803Notes

Reaction equation

HRID 2100803 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[CH3:18][CH:19]([OH:21])[CH3:20]>>[CH:19]([O:21][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1)([CH3:20])[CH3:18]

Participants

3

Reactant 2

HCID 3776IsopropanolHCID 178478391HCID 178478391, compound

Product 1

HCID 178458944HCID 178458944, compound

Procedure

Similar procedure as described in example 10 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and propan-2-ol to give (1-isopropoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine. LC-MS m/e 269(MH+).

Sources & evidence

ORD record
ord-41932c3da8d14799a9614006b0f60a17
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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