HCID 57799548, compound → HCID 57799622, compound

HRID 2100811Notes

Reaction equation

HRID 2100811 reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[C:18]([CH3:20])[NH:17][N:16]=2)[N:3]=1>CC(O)C>[CH:7]([O:12][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[C:18]([CH3:20])[NH:17][N:16]=2)[N:3]=1)([CH3:8])[CH3:6]

Participants

3

Reactant 1

HCID 57799548HCID 57799548, compound

Product 1

HCID 57799622HCID 57799622, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 10 was used, starting from propan-2-ol and (1-chloro-5-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (1-isopropoxy-5-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 313(MH+).

Sources & evidence

ORD record
ord-c189563fa83b4776ac9963cf2a2730fb
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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