HCID 57799766, compound → HCID 57799694, compound

HRID 2100833Notes

Reaction equation

HRID 2100833 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1>CC(O)C>[CH:9]([O:12][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1)([CH3:10])[CH3:8]

Participants

3

Reactant 1

HCID 57799766HCID 57799766, compound

Product 1

HCID 57799694HCID 57799694, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 10 was used, starting from propan-2-ol and (1-chloro-6,7-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (1-isopropoxy-6,7-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 343(MH+).

Sources & evidence

ORD record
ord-72826a117d334c4299e2d0801556a438
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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