4-Chlorophenol → HCID 57799836, compound

HRID 2100844Notes

Reaction equation

HRID 2100844 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Cl[C:10]1[C:19]2[C:14](=[C:15]([O:22][CH3:23])[C:16]([O:20][CH3:21])=[CH:17][CH:18]=2)[CH:13]=[C:12]([NH:24][C:25]2[CH:29]=[C:28]([CH3:30])[NH:27][N:26]=2)[N:11]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:10]2[C:19]3[C:14](=[C:15]([O:22][CH3:23])[C:16]([O:20][CH3:21])=[CH:17][CH:18]=3)[CH:13]=[C:12]([NH:24][C:25]3[CH:29]=[C:28]([CH3:30])[NH:27][N:26]=3)[N:11]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 46844-ChlorophenolHCID 57799659HCID 57799659, compound

Product 1

HCID 57799836HCID 57799836, compound

Procedure

Similar procedure as described in example 10 was used, starting from 4-chloro-phenol and (1-Chloro-5,6-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give [1-(4-chloro-phenoxy)-5,6-dimethoxy-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 411 (MH+).

Sources & evidence

ORD record
ord-307e11ecc80c41a0925ef09467e3f443
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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