2-Chlorophenol → HCID 178478045, compound

HRID 2100861Notes

Reaction equation

HRID 2100861 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[Cl:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[OH:25]>>[Cl:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[O:25][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1

Participants

3

Reactant 2

HCID 72452-ChlorophenolHCID 178478391HCID 178478391, compound

Product 1

HCID 178478045HCID 178478045, compound

Procedure

Similar procedure as described in example 10 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 2-chloro-phenol to give [1-(2-chloro-phenoxy)-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine. LC-MS m/e 337(MH+).

Sources & evidence

ORD record
ord-7ef4a304bc3d4e88b06db747a02be5fc
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

Loading…