HCID 178487533, compound → HCID 178487703, compound

HRID 2100877Notes

Reaction equation

HRID 2100877 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[CH:18][NH:17][N:16]=2)[N:3]=1>CC(O)C>[CH:8]([O:12][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[CH:18][NH:17][N:16]=2)[N:3]=1)([CH3:9])[CH3:7]

Participants

3

Reactant 1

HCID 178487533HCID 178487533, compound

Product 1

HCID 178487703HCID 178487703, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 10 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and propan-2-ol to give (1-isopropoxy-6-methoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine. LC-MS m/e 299(MH+).

Sources & evidence

ORD record
ord-2c2f37e720f54817b19cb336f8d6dadf
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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