HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenylboronic acid → [1-(4-chloro-phenyl)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 57799635 | — |
| Product | [1-(4-chloro-phenyl)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 23633640 | — |
Reaction Steps
Similar procedure as described in example 131 was used, starting from (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and 4-chloro-Phenylboronic acid to give [1-(4-chloro-phenyl)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 335(MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-816a7fe2b5e04145b4d493c76a1a99c7 |
| Source note | uspto-grants-2009_08 |