Phenylboronic Acid → HCID 178420157, compound

HRID 2100965Notes

Reaction equation

HRID 2100965 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[C:18]1(B(O)O)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[C:18]1([C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH:5]=[C:4]([NH:12][C:13]3[CH:17]=[CH:16][NH:15][N:14]=3)[N:3]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 178478391HCID 178478391, compound

Product 1

HCID 178420157HCID 178420157, compound

Procedure

Similar procedure as described in example 131 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and phenylboronic acid to give (1-phenyl-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine. LC-MS m/e 287(MH+).

Sources & evidence

ORD record
ord-7648f25fe9474af6a149330040b8d90f
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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