Dimethylamine, hydrochloride → HCID 57799563, compound

HRID 2101060Notes

Reaction equation

Cl.[CH3:2][NH:3][CH3:4].[CH3:5][O:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][CH:16]=1)[C:13]([C:17]([OH:19])=O)=[N:12][C:11]([NH:20][C:21]1[CH:25]=[C:24]([CH3:26])[NH:23][N:22]=1)=[CH:10]2>>[CH3:2][N:3]([CH3:4])[C:17]([C:13]1[C:14]2[C:9](=[CH:8][C:7]([O:6][CH3:5])=[CH:16][CH:15]=2)[CH:10]=[C:11]([NH:20][C:21]2[CH:25]=[C:24]([CH3:26])[NH:23][N:22]=2)[N:12]=1)=[O:19]

Participants

Reactant 2

HCID 10473Dimethylamine, hydrochloride

HCID 57799594HCID 57799594, compound

Product 1

HCID 57799563HCID 57799563, compound

Procedure

Similar procedure as described in example 317 was used, starting from dimethyl-amine hydrochloride and 6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-1-carboxylic acid to give 6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-1-carboxylic acid dimethylamide. LC-MS: m/e 326 (MH+).

Sources & evidence

ORD record: ord-9bdd2b1b1df14a8f8f8a365261b9d4be
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07572809B2

Reaction notes

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