HCID 57799781, compound → HCID 57799497, compound

HRID 2101064Notes

Reaction equation

HRID 2101064 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH:22]3[CH2:24][CH2:23]3)[NH:19][N:18]=2)[N:3]=1>CC(O)C>[CH:22]1([C:20]2[NH:19][N:18]=[C:17]([NH:16][C:4]3[N:3]=[C:2]([O:12][CH:9]([CH3:10])[CH3:8])[C:11]4[C:6]([CH:5]=3)=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=4)[CH:21]=2)[CH2:24][CH2:23]1

Participants

3

Reactant 1

HCID 57799781HCID 57799781, compound

Product 1

HCID 57799497HCID 57799497, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 10 was used, starting from (1-Chloro-6,7-dimethoxy-isoquinolin-3-yl)-(5-cyclopropyl-1H-pyrazol-3-yl)-amine and propan-2-ol to give (5-Cyclopropyl-1H-pyrazol-3-yl)-(1-isopropoxy-6,7-dimethoxy-isoquinolin-3-yl)-amine. LC-MS m/e 369(MH+).

Sources & evidence

ORD record
ord-a9e7242f7e8a4288be1a074350d696b0
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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