HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 136055520, compound → HCID 136055519, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 136055520 | HCID 136055520 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 136055519 | HCID 136055519 | 79.4% |
Reaction Steps
The mixture of 1-Isopropenyl-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-6-ol (100 mg) and 10% Pd/C (15 mg) was sealed in high-pressure bottle under 40 psi H2 pressure and stirred overnight at room temperature. Then the mixture was filtered, and the filtrate was evaporated to give 1-Isopropyl-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-6-ol (80 mg) as oil. LC-MS: m/e 283 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-587ee1590abc4636a3e404591911f113 |
| Source note | uspto-grants-2009_08 |