HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 5-Benzyloxy-6-methoxy-1-indanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one | HCID 14763395 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-Benzyloxy-6-methoxy-1-indanone | HCID 14763396 | — |
Reaction Steps
The mixture of 5-Hydroxy-6-methoxy-indan-1-one (2.1 g), K2CO3 (3.3 g), acetone (30 ml) and benzyl bromide was heated to reflux for 5 hours. The mixture was filtered and the filtrate was evaporated to oil. The oil was treated with diethyl ether (50 ml) and the solid was collected to give 5-Benzyloxy-6-methoxy-indan-1-one (3 g). LC-MS: m/e 269 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-49abdba8cfdf48d58e84817987cf00a5 |
| Source note | uspto-grants-2009_08 |