反应详情

The mixture of 5-Hydroxy-6-methoxy-indan-1-one (2.1 g), K2CO3 (3.3 g), acetone (30 ml) and benzyl bromide was heated to reflux for 5 hours. The mixture was filtered and the filtrate was evaporated to oil. The oil was treated with diethyl ether (50 ml) and the solid was collected to give 5-Benzyloxy-6-methoxy-indan-1-one (3 g). LC-MS: m/e 269 (MH+).

1. temperaturewas heated
2. temperatureto reflux for 5 hours
3. filtrationThe mixture was filtered
4. customthe filtrate was evaporated to oil
5. additionThe oil was treated with diethyl ether (50 ml)
6. customthe solid was collected