HCID 57799845, compound → HCID 57799814, compound

HRID 2101124Notes

Reaction equation

HRID 2101124 reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([CH3:14])[C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:15][C:16]2[CH:20]=[C:19]([CH3:21])[NH:18][N:17]=2)[N:3]=1>CC(O)C>[CH:8]([O:12][C:2]1[C:11]2[C:6](=[C:7]([CH3:14])[C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:15][C:16]2[CH:20]=[C:19]([CH3:21])[NH:18][N:17]=2)[N:3]=1)([CH3:9])[CH3:7]

Participants

3

Reactant 1

HCID 57799845HCID 57799845, compound

Product 1

HCID 57799814HCID 57799814, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in the example 10 was used, starting from (1-Chloro-6-methoxy-5-methyl-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and 2-propanol to give 5 mg of (1-Isopropoxy-6-methoxy-5-methyl-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine as a yellow solid. LC-MS m/e 327 (MH+).

Sources & evidence

ORD record
ord-1ac9b0b0fb5742ab9b5e8cef877c6459
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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