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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101126Generated: October 26, 2026

3-cyclopropyl-1H-pyrazol-5-amine → HCID 178486650, compound

https://huagongshe.com/reaction/2101126

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-cyclopropyl-1H-pyrazol-5-amineHCID 2758014—
Reactant2-Cyanomethyl-5-fluoro-4-methoxy-benzoic acidHCID 57799877—
ProductHCID 178486650HCID 178486650—

Reaction Steps

Similar procedure as described in example 9B was used, starting from 2-Cyanomethyl-5-fluoro-4-methoxy-benzoic acid (1.75 g), 3-amino-5-cyclopropylpyrazol, to give 3-(5-Cyclopropyl-1H-pyrazol-3-ylamino)-7-fluoro-6-methoxy-isoquinolin-1-ol. LC-MS: m/e 315 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-1810d54ddec741f6a5f5b69a8b59d5fd
Source noteuspto-grants-2009_08