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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101127Generated: November 2, 2026

HCID 57799679, compound → (5-Cyclopropyl-1H-pyrazol-3-yl)-(7-fluoro-1-isopropoxy-6-methoxy-isoquinolin-3-yl)-amine

https://huagongshe.com/reaction/2101127

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57799679HCID 57799679—
SolventIsopropanolHCID 3776—
Product(5-Cyclopropyl-1H-pyrazol-3-yl)-(7-fluoro-1-isopropoxy-6-methoxy-isoquinolin-3-yl)-amineHCID 57799643—

Reaction Steps

Similar procedure as described in example 376 was used, starting from isopropanol, (1-Chloro-7-fluoro-6-methoxy-isoquinolin-3-yl)-(5-cyclopropyl-1H-pyrazol-3-yl)-amine to give (5-Cyclopropyl-1H-pyrazol-3-yl)-(7-fluoro-1-isopropoxy-6-methoxy-isoquinolin-3-yl)-amine. LC-MS: m/e 357(MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-02704806e6344c19b91bc0a0d7fa7609
Source noteuspto-grants-2009_08