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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101138Generated: October 31, 2026

1H-Pyrazol-3-amine, 5-methyl- → HCID 178486774, compound

https://huagongshe.com/reaction/2101138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Pyrazol-3-amine, 5-methyl-HCID 93146—
Reactant3-Chloro-2-cyanomethyl-4,5-dimethoxy-benzoic acidHCID 57799603—
SolventAcetic AcidHCID 176—
ProductHCID 178486774HCID 178486774—

Reaction Steps

Similar procedure as described in example 9B was used, starting from 3-Chloro-2-cyanomethyl-4,5-dimethoxy-benzoic acid, 3-amino-5-methylpyrazol and acetic acid to give 5-Chloro-6,7-dimethoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-1-ol. LC-MS: m/e 335 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-a1524193587547f5980653257cf177f2
Source noteuspto-grants-2009_08