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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101157Generated: October 31, 2026

1-(2-Methoxyethyl)piperazine → [1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-6-yl]-[4-(2-methoxy-ethyl)-piperazin-1-yl]-methanone

https://huagongshe.com/reaction/2101157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Methoxyethyl)piperazineHCID 2734638—
Reactant1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-6-carboxylic acidHCID 57799470—
Product[1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-6-yl]-[4-(2-methoxy-ethyl)-piperazin-1-yl]-methanoneHCID 57799798—

Reaction Steps

Similar procedure as described in example 384 was used, starting from 1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-6-carboxylic acid and 1-(2-Methoxy-ethyl)-piperazine to give [1-Isopropoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinolin-6-yl]-[4-(2-methoxy-ethyl)-piperazin-1-yl]-methanone. LC-MS: m/e 453 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-5adfc910b31f40bcbba320a500a1ef60
Source noteuspto-grants-2009_08