HCID 57799586, compound → HCID 57799619, compound
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:17][CH2:18][CH2:19][O:20][CH3:21])=[C:9]([O:12][CH2:13][CH2:14][O:15][CH3:16])[CH:10]=2)[CH:5]=[C:4]([NH:22][C:23]2[CH:27]=[C:26]([CH3:28])[NH:25][N:24]=2)[N:3]=1>C(O)(C)C>[CH:9]([O:12][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:17][CH2:18][CH2:19][O:20][CH3:21])=[C:9]([O:12][CH2:13][CH2:14][O:15][CH3:16])[CH:10]=2)[CH:5]=[C:4]([NH:22][C:23]2[CH:27]=[C:26]([CH3:28])[NH:25][N:24]=2)[N:3]=1)([CH3:10])[CH3:8]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Similar procedure as described in example 400 was used, starting from isopropyl alcohol and [1-Chloro-6,7-bis-(2-methoxy-ethoxy)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine (Example 9E) to give [1-Isopropoxy-6,7-bis-(2-methoxy-ethoxy)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS: m/e 431(MH+).
Sources & evidence
- ORD record
- ord-e5d63e37c3fe426086b2dedd4fb0b2b2
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07572809B2
Reaction notes
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