HCID 57799710, compound → HCID 57799664, compound

HRID 2101177Notes

Reaction equation

HRID 2101177 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[CH:9][C:10]=2[O:12][CH3:13])[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1>C(O)(C)C>[CH:10]([O:12][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[CH:9][C:10]=2[O:12][CH3:13])[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1)([CH3:11])[CH3:9]

Participants

3

Reactant 1

HCID 57799710HCID 57799710, compound

Product 1

HCID 57799664HCID 57799664, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 400 was used, starting from isopropyl alcohol and (1-Chloro-6,8-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine (example 9F) to give (1-Isopropoxy-6,8-dimethoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS: m/e 343(MH+).

Sources & evidence

ORD record
ord-5ab19738b23d4e44bb50234e541124a6
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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