HCID 57799501, compound → HCID 57799600, compound

HRID 2101179Notes

Reaction equation

HRID 2101179 reaction equation
[CH3:1][N:2]([CH3:25])[C:3]([C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[C:10]([NH:16][C:17]3[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=3)[N:11]=[C:12]2Cl)=[CH:7][C:6]=1[O:23][CH3:24])=[O:4]>C(O)(C)C>[CH3:1][N:2]([CH3:25])[C:3]([C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[C:10]([NH:16][C:17]3[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=3)[N:11]=[C:12]2[O:23][CH:6]([CH3:7])[CH3:5])=[CH:7][C:6]=1[O:23][CH3:24])=[O:4]

Participants

3

Reactant 1

HCID 57799501HCID 57799501, compound

Product 1

HCID 57799600HCID 57799600, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 400 was used, starting from isopropyl alcohol and 1-Chloro-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-7-carboxylic acid dimethylamide (example 9G) to give 1-Isopropoxy-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-7-carboxylic acid dimethylamide. LC-MS: m/e 384(MH+).

Sources & evidence

ORD record
ord-1850a61e7fb14b9e80c96cbedf4087d7
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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