Cyclopentanol → HCID 57799528, compound

HRID 2101181Notes

Reaction equation

[CH:1]1([OH:6])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:7][N:8]([CH3:31])[C:9]([C:11]1[CH:20]=[C:19]2[C:14]([CH:15]=[C:16]([NH:22][C:23]3[CH:27]=[C:26]([CH3:28])[NH:25][N:24]=3)[N:17]=[C:18]2Cl)=[CH:13][C:12]=1[O:29][CH3:30])=[O:10]>>[CH3:31][N:8]([CH3:7])[C:9]([C:11]1[CH:20]=[C:19]2[C:14]([CH:15]=[C:16]([NH:22][C:23]3[CH:27]=[C:26]([CH3:28])[NH:25][N:24]=3)[N:17]=[C:18]2[O:6][CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:13][C:12]=1[O:29][CH3:30])=[O:10]

Participants

Reactant 2

HCID 7298Cyclopentanol

HCID 57799501HCID 57799501, compound

Product 1

HCID 57799528HCID 57799528, compound

Procedure

Similar procedure as described in example 400 was used, starting from cyclopentanol and of 1-Chloro-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-7-carboxylic acid dimethylamide to give 1-Cyclopentyloxy-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-7-carboxylic acid dimethylamide, LC-MS: m/e 410(MH+).

Sources & evidence

ORD record: ord-caa491bd583d4ba884eabcb3e1fde614
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07572809B2

Reaction notes

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