HCID 57799589, compound → HCID 68858208, compound

HRID 2101182Notes

Reaction equation

HRID 2101182 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([C:12]#[N:13])[CH:10]=2)[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1>C(O)(C)C>[CH:8]([O:14][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([C:12]#[N:13])[CH:10]=2)[CH:5]=[C:4]([NH:16][C:17]2[CH:21]=[C:20]([CH3:22])[NH:19][N:18]=2)[N:3]=1)([CH3:9])[CH3:7]

Participants

3

Reactant 1

HCID 57799589HCID 57799589, compound

Product 1

HCID 68858208HCID 68858208, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Similar procedure as described in example 400 was used, starting from isopropyl alcohol and 1-Chloro-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-7-carbonitrile (example 9H) to give 1-Isopropoxy-6-methoxy-3-(5-methyl-1H-pyrazol-3-ylamino)-isoquinoline-7-carbonitrile. LC-MS: m/e 338(MH+).

Sources & evidence

ORD record
ord-6f6f1c270b83407bad64d6e04c8eb7db
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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