Hydrochloric Acid → HCID 10246188, compound

HRID 2101217Notes

Reaction equation

HRID 2101217 reaction equation
[NH2:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH:9]([CH:13]([SH:24])[CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22]C)=[CH:18][CH:17]=2)[C:10]([OH:12])=[O:11])=[CH:4][CH:3]=1.Cl>>[NH2:1][C:2]1[N:7]=[CH:6][C:5]([CH2:8][CH:9]([CH:13]([SH:24])[CH2:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]([OH:22])=[CH:20][CH:21]=2)[C:10]([OH:12])=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10088980HCID 10088980, compound

Product 1

HCID 10246188HCID 10246188, compound

Procedure

2-[(6-Aminopyridin-3-yl)methyl]-5-(4-hydroxyphenyl)-3-mercaptopentanoic acid was synthesized from 2-[(6-aminopyridin-3-yl)methyl]-3-mercapto-5-(4-methoxyphenyl)pentanoic acid using standard conditions for the methoxy group hydrolysis (concentrated aqueous hydrochloric acid at reflux under argon for 24 h).

Sources & evidence

ORD record
ord-f1fbb86450bc46eca465bcf0eb3e3b09
Source dataset
uspto-grants-2009_08
Patent number
US07572817B2

Reaction notes

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