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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101263Generated: October 30, 2026

5-chloro-6-fluoro-1H-indole-7-carboxylic acid → 5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(3,4-dichloro-phenyl)-ethyl]-(4-tri-methylsilanyl-benzyl)-amide

https://huagongshe.com/reaction/2101263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-chloro-6-fluoro-1H-indole-7-carboxylic acidHCID 25113647—
Reactant[2-(3,4-Dichloro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amineHCID 57438504—
Product5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(3,4-dichloro-phenyl)-ethyl]-(4-tri-methylsilanyl-benzyl)-amideHCID 24779978—

Reaction Steps

5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(3,4-dichloro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amide was prepared in analogy to example 1 from 5-chloro-6-fluoro-1H-indole-7-carboxylic acid and [2-(3,4-dichloro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amine. MS (ISP) 547.2/549.3/551.3 (96/100/37) (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572823B2
Source datasetuspto-grants-2009_08
ORD IDord-ac9208f315d9428cbd478fef6af1b4de
Source noteuspto-grants-2009_08