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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2101269Generated: November 1, 2026

5-chloro-6-fluoro-1H-indole-7-carboxylic acid → 5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(4-fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amide

https://huagongshe.com/reaction/2101269

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-chloro-6-fluoro-1H-indole-7-carboxylic acidHCID 25113647—
Reactant[2-(4-Fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amineHCID 57438507—
Product5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(4-fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amideHCID 24779980—

Reaction Steps

5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(4-fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amide was prepared in analogy to example 1 from 5-chloro-6-fluoro-1H-indole-7-carboxylic acid and [2-(4-fluoro-phenyl)-ethyl]-(4-trimethylsilanyl-benzyl)-amine. MS (ISP) 497.4/499.3 (100/48) (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572823B2
Source datasetuspto-grants-2009_08
ORD IDord-d95c64a3110b43a4b9e7fa0090ddc097
Source noteuspto-grants-2009_08