8-bromo-7-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one → 6-bromo-7-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

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Reaction Steps

The title compound (125 mg, 96% yield) as a pale yellow solid was prepared from 3-bromo-4-(4-chlorophenyl)-6-hydrazinyl-2-methylpyridine (120 mg, 0.384 mmol) by procedures analogous to those used for the preparation of 8-bromo-7-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one. HPLC/MS: retention time=3.65 min, [M+H]+=338.2.

Provenance & Evidence