HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → 2-(4-Fluoro-phenoxymethyl)-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | 2-(3-methoxy-phenoxymethyl)-1H-imidazole | HCID 57801492 | — |
| Product | 2-(4-Fluoro-phenoxymethyl)-1H-imidazole | HCID 57801527 | — |
Reaction Steps
2-(4-Fluoro-phenoxymethyl)-1H-imidazole was prepared following a similar procedure for the preparation of 2-(3-Methoxy-phenoxymethyl)-1H-imidazole (see Example 18) using 4-fluorophenol in place of 3-methoxyphenol to provide a white solid (1.69 g, 85% for 2 steps); ESI MS m/z 193 [C10H9FN2O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572921B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-e9d2e7b1cd004b4c83a166cb96acf7d1 |
| Source note | uspto-grants-2009_08 |