Methylamine → HCID 9944901, compound

HRID 2101701Notes

Reaction equation

[CH3:1][NH2:2].[CH3:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:11]=[C:12]([C:23](O)=[O:24])[N:13]([CH3:22])[C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[CH:6][CH:5]=1>>[CH3:1][NH:2][C:23]([C:12]1[N:13]([CH3:22])[C:14]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[C:10]([C:7]2[CH:6]=[CH:5][C:4]([CH3:3])=[CH:9][CH:8]=2)[N:11]=1)=[O:24]

Participants

Reactant 2

HCID 6329Methylamine

HCID 22066080HCID 22066080, compound

Product 1

HCID 9944901HCID 9944901, compound

Procedure

Using essentially the same procedure as Example 9, Step B, but using methylamine (0.20 mL of 2N methylamine in THF), 4,5-di-(4-methylphenyl)-1-methylimidazole-2-carboxylic acid (25 mg, 0.08 mmol) from Example 9, Step A was converted to the title compound.

Sources & evidence

ORD record: ord-075aa85e552a4d78a82ca9f7d827e646
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07572785B2

Reaction notes

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