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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2102010Generated: October 25, 2026

2-(Bromomethyl)-5-(trifluoromethyl)furan → 4-Chloro-2-ethyl-1-{[5-(trifluoromethyl)-2-furanyl]methyl}-1H-benzimidazole-5-carbonitrile

https://huagongshe.com/reaction/2102010

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Bromomethyl)-5-(trifluoromethyl)furanHCID 2794605—
Reactant4-chloro-2-ethyl-1H-benzimidazole-5-carbonitrileHCID 67404902—
Product4-Chloro-2-ethyl-1-{[5-(trifluoromethyl)-2-furanyl]methyl}-1H-benzimidazole-5-carbonitrileHCID 67407575—

Reaction Steps

Synthesized as described in Example 197B from 4-chloro-2-ethyl-1H-benzimidazole-5-carbonitrile and 2-(bromomethyl)-5-(trifluoromethyl)furan: MS (ESI) m/z 354 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572820B2
Source datasetuspto-grants-2009_08
ORD IDord-915c196717aa41e9a52244d2983a7219
Source noteuspto-grants-2009_08