Pyridine → N-(5-nitrobenzothiazol-2-yl)benzamide

Participants

Role	Name	HCID	Charge
Reactant	Pyridine	HCID 1049	—
Reactant	Benzoyl chloride	HCID 7412	—
Reactant	5-Nitro-1,3-benzothiazol-2-amine	HCID 2754759	—
Solvent	Water	HCID 962	—
Product	N-(5-nitrobenzothiazol-2-yl)benzamide	HCID 13481965	78.5%

Reaction Conditions

Temperature	60 °C

Reaction Steps

A mixture of 2-amino-5-nitrobenzothiazole (1.52 g, 7.8 mmol), benzoyl chloride (1.36 mL, 11.7 mmol) and pyridine (15 mL) was heated to 60° C. for 24 h. The mixture was poured into water (250 mL), and the resulting precipitate was separated by filtration to yield N-(5-nitrobenzothiazol-2-yl)benzamide (1:83 g, 6.12 mmol, 78%) as a yellow solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07576090B2
Source dataset	uspto-grants-2009_08
ORD ID	ord-228d90cf4e6341329780bda850a50e07
Source note	uspto-grants-2009_08