Hydroxide → 5-Amino-2,4-difluorophenol

HRID 210285Notes

Reaction equation

HRID 210285 reaction equation
[CH3:13][CH2:14][O:15][C:16]([CH3:17])=[O:18].[F:1][c:2]1[c:3]([OH:12])[cH:4][c:5]([N+:9]([O-:10])=[O:11])[c:6]([F:8])[cH:7]1.[OH-:19].[OH-:21].[Pd+2:20]>>[F:1][c:2]1[c:3]([OH:12])[cH:4][c:5]([NH2:9])[c:6]([F:8])[cH:7]1

Participants

5

Reactant 4

HCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 109210242,4-Difluoro-5-nitrophenol

Product 1

HCID 27829995-Amino-2,4-difluorophenol

Sources & evidence

ORD record
ord-5b08ce4a81d7480e99c77aa3c128b78b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…