Sodium borohydride → HCID 69055644, compound

HRID 2103020Notes

Reaction equation

HRID 2103020 reaction equation
[OH:1][C:2]1[C:3]([CH3:17])=[C:4]2[C:12](=[CH:13][C:14]=1[CH3:15])[O:11][C:7]1([CH2:10][CH2:9][CH2:8]1)[CH2:6][C:5]2=[O:16].[BH4-].[Na+]>CO>[CH3:17][C:3]1[C:2]([OH:1])=[C:14]([CH3:15])[CH:13]=[C:12]2[C:4]=1[CH:5]([OH:16])[CH2:6][C:7]1([O:11]2)[CH2:8][CH2:9][CH2:10]1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 69054367HCID 69054367, compound

Product 1

HCID 69055644HCID 69055644, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 6-hydroxy-5,7-dimethylspiro[chromene-2,1′-cyclobutan]-4(3H)-one,( 345 mg) in methanol (5 mL) was added sodium borohydride (65 mg). The mixture was stirred at room temperature for 30 min. The mixture was concentrated and the methanol removed to give 5,7-dimethyl-3,4-dihydrospiro[chromene-2,1′-cyclobutane]-4,6-diol.

Workup

  1. concentrationThe mixture was concentrated
  2. customthe methanol removed

Sources & evidence

ORD record
ord-c5a29e90eb9643d18d0e8107b8db69f8
Source dataset
uspto-grants-2009_08
Patent number
US07576094B2

Reaction notes

Loading…