Chlorosuccinimide → HCID 22475115, compound

HRID 2103139Notes

Reaction equation

HRID 2103139 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1([C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][C:23]=2[F:29])[O:13][C:12]2[CH:14]=[C:15]([F:21])[C:16]([S:18]([OH:20])=[O:19])=[CH:17][C:11]=2[O:10]1.[Cl:30]N1C(=O)CCC1=O>C(Cl)(Cl)Cl>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1([C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][C:23]=2[F:29])[O:13][C:12]2[CH:14]=[C:15]([F:21])[C:16]([S:18]([Cl:30])(=[O:20])=[O:19])=[CH:17][C:11]=2[O:10]1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 22475230HCID 22475230, compound

Product 1

HCID 22475115HCID 22475115, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of 2,2-bis-(2,4-difluoro-phenyl)-6-fluoro-benzo[1,3]dioxole-5 sulfinic acid (3.2 g, 7 mmol) in chloroform (25 mL) was added N-chlorosuccinimide (1.0 g, 7 mmol, 1.0 eq.) at 20° C. After 40 min, the reaction mixture was filtered and the filtrate was evaporated. The residue was suspended in dichloromethane, dried over sodium sulfate and the solvent was removed in vacuo, affording the title product as a light yellow gum.

Workup

  1. filtrationthe reaction mixture was filtered
  2. customthe filtrate was evaporated
  3. dry with materialdried over sodium sulfate
  4. customthe solvent was removed in vacuo

Sources & evidence

ORD record
ord-1b6ebc99fe254a109cc81dab00f7680d
Source dataset
uspto-grants-2009_08
Patent number
US07576088B2

Reaction notes

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