Methanol → HCID 67084469, compound

HRID 2103596Notes

Reaction equation

HRID 2103596 reaction equation
[CH2:1]([O:3][C:4](=[O:20])/[C:5](/[C:12]1[CH:17]=[CH:16][C:15](SC)=[CH:14][CH:13]=1)=[CH:6]/[CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])[CH3:2].O[O:22][S:23]([O-:25])=O.[K+].[CH3:27]O>>[CH2:1]([O:3][C:4](=[O:20])/[C:5](/[C:12]1[CH:13]=[CH:14][C:15]([S:23]([CH3:27])(=[O:25])=[O:22])=[CH:16][CH:17]=1)=[CH:6]/[CH2:7][C:8]([CH3:10])([CH3:11])[CH3:9])[CH3:2]

Participants

4

Reactant 3

HCID 887MethanolHCID 23707502Potassium hydroxy sulfiteHCID 67084600HCID 67084600, compound

Product 1

HCID 67084469HCID 67084469, compound

Procedure

Following the method of example 54d, oxidation of (E)-5,5-dimethyl-2-(4-methylsulfanyl-phenyl)-hex-2-enoic acid ethyl ester (680 mg, 2.34 mmol) with oxone® (1.86 g, 3.0 mmol) in methanol gives the title compound as a yellow oil (720 mg). MS (m/e): 325 (M+H).

Sources & evidence

ORD record
ord-574c3a1e12e5496190bd373986feb9a9
Source dataset
uspto-grants-2009_08
Patent number
US07576108B2

Reaction notes

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