1,1,1-Trifluoro-2,4-pentanedione → HCID 11710932, compound

HRID 2104142Notes

Reaction equation

HRID 2104142 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=O.[F:17][C:18]([F:26])([F:25])[C:19](=[O:24])[CH2:20][C:21](=O)[CH3:22]>CCCCCCC.C(OCC)(=O)C>[Br:8][C:5]1[CH:4]=[C:3]2[C:2](=[CH:7][CH:6]=1)[N:1]=[C:21]([CH3:22])[C:20]([C:19](=[O:24])[C:18]([F:26])([F:25])[F:17])=[C:9]2[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 739431,1,1-Trifluoro-2,4-pentanedioneHCID 996772-Amino-5-bromobenzophenone

Product 1

HCID 11710932HCID 11710932, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 21899848Ethylacetate heptaneSolvent

Procedure

The title compound was prepared from (2-Amino-5-bromo-phenyl)-phenyl-methanone [example A16] and 1,1,1-trifluoro-2,4-pentanedione according to the procedure of example 1, except that heptane/ethyl acetate (10:1) was used. Yield: 50%; MS: m/z=392/394 (M).

Sources & evidence

ORD record
ord-61fbbd4bd1c0492781fb2a19637495ed
Source dataset
uspto-grants-2009_08
Patent number
US07576217B2

Reaction notes

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