Acetylacetone → HCID 11509149, compound

HRID 2104146Notes

Reaction equation

HRID 2104146 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]([F:12])([F:11])[F:10])=[CH:4][C:3]=1[C:13]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)=O.[C:22]([CH2:25][C:26](=O)[CH3:27])(=[O:24])[CH3:23]>CCCCCCC.C(OCC)(=O)C>[Cl:21][C:18]1[CH:19]=[CH:20][C:15]([C:13]2[C:3]3[C:2](=[CH:7][CH:6]=[C:5]([O:8][C:9]([F:12])([F:11])[F:10])[CH:4]=3)[N:1]=[C:26]([CH3:27])[C:25]=2[C:22](=[O:24])[CH3:23])=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 31261AcetylacetoneHCID 68405958HCID 68405958, compound

Product 1

HCID 11509149HCID 11509149, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 21899848Ethylacetate heptaneSolvent

Procedure

The title compound was prepared from (2-Amino-5-trifluoromethoxy-phenyl)-(4-chloro-phenyl)-methanone [example A3] and acetylacetone according to the method of example 1, except that heptane/ethyl acetate (1:2) was used. Yield: 61%. MS: m/z=379 (M).

Sources & evidence

ORD record
ord-287e679406e24819ac0a8608bef8b150
Source dataset
uspto-grants-2009_08
Patent number
US07576217B2

Reaction notes

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