Piperidine → HCID 11703428, compound

HRID 2104194Notes

Reaction equation

HRID 2104194 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH3:12])[C:6]([C:13]([CH:15]1[CH2:17][CH2:16]1)=[O:14])=[C:5]2[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[NH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH:15]1([C:13]([C:6]2[C:7]([CH3:12])=[N:8][C:9]3[C:4]([C:5]=2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:3][C:2]([N:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)=[CH:11][CH:10]=3)=[O:14])[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 11632004HCID 11632004, compound

Product 1

HCID 11703428HCID 11703428, compoundYield 64%

Procedure

The title compound was prepared from [(6-Bromo-2-methyl-4-phenyl-quinolin-3-yl)-cyclopropyl-methanone [example 55] and piperidine according to the procedure of example 51. Yield: 64%; MS: m/z=371 (M+H).

Sources & evidence

ORD record
ord-4d9951b6389948e29199f64cdd47edbe
Source dataset
uspto-grants-2009_08
Patent number
US07576217B2

Reaction notes

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