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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104304Generated: October 30, 2026

5-Methoxyindole → 5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole

https://huagongshe.com/reaction/2104304

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-MethoxyindoleHCID 13872—
ReactantPiperidine-4,4-diolHCID 3853601—
Product5-Methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indoleHCID 108029—

Reaction Steps

The experimental protocol used is described in the literature (Eur. J. Med. Chem. (1987) 22, 33-43), starting from 5-methoxy-1H-indole and 4,4-piperidinediol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576241B2
Source datasetuspto-grants-2009_08
ORD IDord-addf11ad33bb4fdb9b18ec2f241f4d05
Source noteuspto-grants-2009_08