4-Chloro-2-nitroaniline → HCID 22934712, compound

HRID 2104417Notes

Reaction equation

HRID 2104417 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.Cl[C:13](=[O:18])[C:14]([O:16]C)=[O:15].[OH-].[Na+:20]>CO>[Na+:20].[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:13](=[O:18])[C:14]([O-:16])=[O:15])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1

Participants

5

Reactant 3

HCID 69794-Chloro-2-nitroanilineHCID 14798Sodium HydroxideHCID 79846Methyl chloroglyoxylate

Product 1

HCID 22934712HCID 22934712, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a manner similar to that described in Referential Example 242, 4-chloro-2-nitroaniline was condensed with methyl chlorooxoacetate. In a manner similar to that described in Referential Example 266, the condensed compound was hydrolyzed. The residue was dissolved in methanol, 1N aqueous sodium hydroxide was added thereto, and the precipitated material was recoverd by filtration, whereby the title compound was obtained.

Workup

  1. filtrationthe precipitated material was recoverd by filtration, whereby the title compound
  2. customwas obtained

Sources & evidence

ORD record
ord-002956499cd447c5a7d6d905badbcea8
Source dataset
uspto-grants-2009_08
Patent number
US07576135B2

Reaction notes

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