4-Fluorobenzoyl chloride → HCID 669228, compound

HRID 2104431Notes

Reaction equation

HRID 2104431 reaction equation
[CH2:1]([O:3][C:4](=[O:11])[CH:5]1[CH2:10][CH2:9][NH:8][CH2:7][CH2:6]1)[CH3:2].[F:12][C:13]1[CH:21]=[CH:20][C:16]([C:17](Cl)=[O:18])=[CH:15][CH:14]=1>>[CH2:1]([O:3][C:4]([CH:5]1[CH2:6][CH2:7][N:8]([C:17](=[O:18])[C:16]2[CH:20]=[CH:21][C:13]([F:12])=[CH:14][CH:15]=2)[CH2:9][CH2:10]1)=[O:11])[CH3:2]

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 669228HCID 669228, compound

Procedure

The method described in Referential Example 492 was performed by use of isonipecotic acid ethyl ester and p-fluorobenzoyl chloride, whereby the title compound was obtained.

Sources & evidence

ORD record
ord-937f2c0d595c4d7dbf211c457650181c
Source dataset
uspto-grants-2009_08
Patent number
US07576135B2

Reaction notes

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