Pyrrolidine → Methyl 4-(pyrrolidine-1-carbonyl)benzoate

HRID 2104432Notes

Reaction equation

HRID 2104432 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:6]Cl.[C:8]([OH:19])(=[O:18])[C:9]1[CH:17]=[CH:16][C:12]([C:13]([OH:15])=O)=[CH:11][CH:10]=1>>[CH3:6][O:19][C:8](=[O:18])[C:9]1[CH:10]=[CH:11][C:12]([C:13]([N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[O:15])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 66962955HCID 66962955, compound

Product 1

HCID 17178210Methyl 4-(pyrrolidine-1-carbonyl)benzoate

Procedure

The method described in Referential Example 492 was performed by use of pyrrolidine and terephthalic acid monomethyl chloride, whereby the title compound was obtained.

Sources & evidence

ORD record
ord-fef95b2cab7b4f73aebb13f9cd3a6d00
Source dataset
uspto-grants-2009_08
Patent number
US07576135B2

Reaction notes

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