Phenyl[4-phenyl-8-(trifluoromethyl)quinolin-3-yl]methanone → 4-(4-Tert-butylphenyl)-3-(pyridin-2-ylmethyl)-8-(trifluoromethyl)quinoline

Participants

Role	Name	HCID	Charge
Reactant	Phenyl[4-phenyl-8-(trifluoromethyl)quinolin-3-yl]methanone	HCID 11360909	—
Reactant	[4-(4-Tert-Butylphenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Pyridin-2-yl)Methanone	HCID 11453296	—
Product	4-(4-Tert-butylphenyl)-3-(pyridin-2-ylmethyl)-8-(trifluoromethyl)quinoline	HCID 66913205	—

Reaction Steps

This compound was prepared using the procedure of Example 31 substituting [4-(4-tert-butylphenyl)-8-(trifluoromethyl)quinolin-3-yl](pyridin-2-yl)methanone. of Example 18 for 2 phenyl[4-phenyl-8-(trifluoromethyl)quinolin-3-yl]methanone. MS (ESI) m/z 421 ([M+H]+); Anal. Calcd for C26H23F3N2: C, 74.27; H, 5.51; N, 6.66. Found: C, 73.94; H, 5.30; N, 6.53.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07576215B2
Source dataset	uspto-grants-2009_08
ORD ID	ord-88908204b773428e889de766e8a77d4b
Source note	uspto-grants-2009_08