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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104528Generated: October 25, 2026

[3-(Hydroxymethyl)phenyl]boronic acid → {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Methanol

https://huagongshe.com/reaction/2104528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[3-(Hydroxymethyl)phenyl]boronic acidHCID 2734662—
Reactant3-Benzyl-4-bromo-8-(trifluoromethyl)quinolineHCID 66913146—
Product{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}MethanolHCID 11223110—

Reaction Steps

This compound was prepared using the procedure of Example 1, step 5 using (3-benzyl-4-bromo-8-(trifluoromethyl)quinoline in place of [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone and 3-(hydroxymethyl)phenylboronic acid in place of phenyl boronic acid; MS (ES) m/z 392.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-3ffb794679574ba8b85a3ea9214dfdf7
Source noteuspto-grants-2009_08