HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → [4-(3-Methylamino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | [4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone | HCID 11326798 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [4-(3-Methylamino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone | HCID 66913517 | — |
Reaction Steps
A solution of [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone (100 mg) and dimethyl sulfate (150 mg) in ethanol was stirred at r.t. for 4 hrs. The solution was concentrated and purified by semi-HPLC to give [4-(3-methylamino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone as a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-63201ac25d7d406a87f902bca4db7987 |
| Source note | uspto-grants-2009_08 |