(1,1'-Biphenyl)-4-carboxaldehyde → HCID 66913842, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.[C:30]1([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[CH:35]=[CH:34][C:33]([CH:36]=O)=[CH:32][CH:31]=1>>[C:30]1([C:38]2[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=2)[CH:31]=[CH:32][C:33]([CH2:36][NH:1][C:2]2[CH:3]=[C:4]([C:8]3[C:17]4[C:12](=[C:13]([C:18]([F:21])([F:19])[F:20])[CH:14]=[CH:15][CH:16]=4)[N:11]=[CH:10][C:9]=3[C:22]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)=[O:23])[CH:5]=[CH:6][CH:7]=2)=[CH:34][CH:35]=1Participants
3
Procedure
The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and biphenyl-4-carbaldehyde according to the procedure of Example 66. MS (ES) m/z 559.2.
Sources & evidence
- ORD record
- ord-2f5e84574b234e37ba19d25b1abcceef
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576215B2
Reaction notes
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