HRID2104565

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2759226

4-(4'-Formyl-3'-methoxy)phenoxy butyric acid

C12H14O5

结构：Nc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1

HCID11326798

未命名化合物

PRODUCTS

生成物

结构：COc1cc(OCCCC(=O)O)ccc1CNc1cccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)c1

HCID66913564

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 4-(4-formyl-3-methoxy-phenoxy)-butyric acid according to the procedure of Example 66. MS (ESI) m/z 613.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8908e746b2db4ebbbd8caec6c50eeb5c
来源数据集: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07576215B2
来源说明: uspto-grants-2009_08

反应 SMILES

[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:17]3[C:12](=[C:13]([C:18]([F:21])([F:20])[F:19])[CH:14]=[CH:15][CH:16]=3)[N:11]=[CH:10][C:9]=2[C:22]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:23])[CH:5]=[CH:6][CH:7]=1.[CH:30]([C:32]1[CH:44]=[CH:43][C:35]([O:36][CH2:37][CH2:38][CH2:39][C:40]([OH:42])=[O:41])=[CH:34][C:33]=1[O:45][CH3:46])=O>>[C:22]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:8]=1[C:4]1[CH:3]=[C:2]([NH:1][CH2:30][C:32]3[CH:44]=[CH:43][C:35]([O:36][CH2:37][CH2:38][CH2:39][C:40]([OH:42])=[O:41])=[CH:34][C:33]=3[O:45][CH3:46])[CH:7]=[CH:6][CH:5]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:21])([F:19])[F:20])(=[O:23])[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1